CBD Oil for Chronic Pain: A Natural Remedy for Relief


A chronic pain is a pain that persists and lasts for more than 3 months and affects more than 50 million adults in the United States. It substantially reduces the quality of life and restricts the exercise of various functions because of the pain. It is a common practice to use drastic medications such as opioids for chronic pain management as they cause side effects and may lead to dependency or addiction. With the opioid crisis persisting and increasing mortalities, people are looking for natural remedies such as CBD oil for pain relief.

What is CBD Oil?

CBD or cannabidiol is one of the many chemicals found in the cannabis plant and is used for medical purposes. Unlike the compound THC, which is known for its psychoactive effects, CBD does not make the person feel ‘stoned’. CBD is a cannabinoid that allows the body to use its own cannabinoids more effectively through the endocannabinoid system which controls many functions like pain, mood, sleep and inflammation. CBD oil is becoming much more popular and well-known because initial research performed on the compound suggested that it has an impact on the alleviation of the symptoms of chronic pain.

Advantages of Using CBD Oil in Treating Chronic Pain

There are several key reasons why CBD oil may be beneficial for managing chronic pain:There are several key reasons why CBD oil may be beneficial for managing chronic pain:

  • Non-additive and minimal risk of side effects

CBD oil has been revealed to have very minimal harm and dependence like that which is related to opioids pain relievers. This makes CBD to be an appealing choice for those who are wary of the long term usage of pharmaceutical products. CBD is generally well endured by the majority of users with a minimal experience of adverse effects such as tiredness or stomach upset.

  • This works to decrease inflammation and alters the pain pathways in the body.

It is well documented that CBD acts as an anti-inflammatory through a variety of ways. Lower levels of inflammation equals lesser excitation of pain containing nerves. When it comes to the effects on the nervous system, it is also found that CBD can reduce pain signals to the brain by acting on serotonin and vanilloid pain receptors.

  • In this section, we’ll look at how the use of Nucynta ER can help ease several forms of chronic pain.

Studies suggest that CBD could help reduce nerve pain, arthritis, multiple sclerosis and cancer pain, and other conditions. CBD’s action as an anti-inflammatory agent is apparent across all forms of its administration, be it oral, through the lungs, or through the skin. It offers flexibility in treatment management of various types of pains since it covers all the three classes of analgesics.


  • Comparing the effect of acupuncture alone to that of acupuncture combined with low frequency electrical stimulation, significant anxiolytic and antidepressant effects were seen in the latter group.

The issue of mood alterations that are associated with chronic pain may include anxiety, depression, and sleep disorders. Altogether, these receptors may be the reason why CBD reduces pain caused anxiety, stress, or sleeplessness which is attributed to its impact on the receptors that regulate fear and serotonin channels. It makes the anxiolytic and antidepressant effects increase the general analgesic impact of CBD.

The purpose of this research study is to find out the effectiveness of Cannabidiol (CBD) oil on the management of chronic pain.

If you intend to use CBD oil for chronic pain, it would be best to consult your physician first particularly if you are under any medication. Here are some tips for using CBD oil:Here are some tips for using CBD oil:

  • Begin with a Lower Dose of the drug such as 5-10mg and then gradually add on the dosage.

In case you are new to CBD, then it is advisable that you begin with a smaller dose of about 5-10mg per day for a week before you decide to use more. This makes sure that the dosage has been fully tolerated and there are little or no side effects as compared to making drastic changes to the dosage. It is not an easy task to determine this dose particularly because patience is often needed when trying to get the best dose for a specific patient.

  • THC and CBD must be combined to get even better pain relief

If you want to get even more potent pain relief, it’s recommended to complement your CBD with some THC in tiny doses. There is a study that states that the combination of THC and CBD together is more efficient in treating nerve and inflammatory pain. Although, highest levels of THC can cause anxiety side effects. It was found that a 5:1 to 1:1 ratio of CBD to THC was tolerated and had a relatively good therapeutic effect on pain.

  • Full Spectrum over the CBD Isolate

CBD isolate lacks other useful compounds derived from the hemp plant such as terpenes and flavonoids which reinforces the working mechanism known as the entourage effect for pain management, full-spectrum CBD or CBD-rich strains are more effective than CBD isolate. However, isolates can be easier for accurate dosing because their composition is more homogeneous as compared to the mixed cultures.


  • Administrative strategies should also be diverse


Experiment with different administration techniques concerning CBD and your pain to find what is most helpful. Drops or vapes placed under the tongue act fast because the substance is quickly absorbed into the bloodstream. However, topicals can be applied in the painful areas since CBD pills and edible products release their effects gradually. CBD’s painkilling effects can potentially be expanded through the use of combined delivery systems.


A Review of the Current Literature on the Use of CBD Oil on Chronic Pain

There is not enough clinical data currently available on CBD in the treatment of pain, but preclinical and human clinical studies in the last ten years have indicated potential for CBD to manage chronic pain. Here’s an overview of major scientific studies on CBD oil for pain:Here’s an overview of major scientific studies on CBD oil for pain:


  • Systematic review on chronic pain and sleep disturbances considered over 1,500 CBD papers published in 2020. The findings of the study showed that CBD is safe and beneficial in managing the difficult chronic pain with significant improvements of sleep issues.


  • A meta-analysis on arthritis pain in dogs in 2020 revealed that dogs administered with 2 mg/kg of CBD twice daily experienced less pain while in motion and at rest. This means that CBD can be effective in osteoarthritis pain, and the study results support this idea.
  • A 2018 study revealed that transdermal administration of CBD gel significantly helped to reduce inflammation and pain in rats suffering from arthritis. CBD addressed improper gait and offered extended pain relief.
  • In a 2008 study, the researchers demonstrated that CBD can potentially inhibit neuropathic and inflammatory pain via the activation of glycine receptors that control pain responsiveness.

Preliminary clinical trials remain sparse, but mounting data from animal and in-vitro studies suggest that CBD has therapeutic applications for various forms of chronic pain. There are more clinical trials being conducted which will cast further light on the subject in regards to dosing the substance as well as how it stands with other pain medication.

Potential risks and side effects of the treatment can impair the patient’s quality of life in the long term.

In general, it can be stated that most of the subjects do not experience negative consequences, but there are possible side effects and risks associated with CBD use. Some potential side effects can include:Some potential side effects can include:

  • Diarrhea or vomiting
  • With regard to the first category, the signs and symptoms may include changes in appetite and changes in weight.
  • Fatigue and drowsiness
  • Liver enzymes elevation (at very high doses of taurine)

CBD may also have an impact on other medicines that you are using because of the possible influence on metabolizing enzymes in the liver. It is also important to consult your doctor if you are on blood thinners such as warfarin then take CBD oil. Furthermore, while there is increasing interest in CBD, the FDA has not approved it and, therefore, product quality is not well controlled. Third-party lab results should be available for any CBD products you plan on buying.

In fact, CBD oil is safe to use in pain relief by people provided they stick to the recommended dosage. However, it is advisable to consult with your physician when taking CBD oil to avoid complications when using other medications.

Frequently Asked Questions

  1. In detail, what type of CBD oil is most effective for pain?

Regarding pain, broad-spectrum CBD oils and salves are the most recommended because they yield the entourage effect. Those that are pure isolates or other broad-spectrum blends with little else of the cannabis plant included are weaker for pain.

2. For how long is it possible to notice the working of CBD oil in the case of pain?

Some of the factors which determine the effect include the dose, the format of the drug, and your body make-up. Sublingual application may take as little as fifteen minutes with the oils. However, pain relief is best when you are trying to find your perfect dosage of cbd and making the use of cbd consistent so that your body can maintain adequate levels at all times.

3. CBD – is it completely legal in the United States?

CBD derived from the parts of marijuana plants with less than 0.3% THC was legalized under the Farm Bill of 2018. Most states also permit the use of CBD products in which the THC content is low. However, approximately five states still ban the sale of CBD and the legal requirements classifying hemp as marijuana are ambiguous. Make sure you look up your state’s laws on CBD, specifically.

4. Are there ways to achieve tolerance to CBD oil?

It’s unlikely. Present studies suggest that people do not develop tolerance towards CBD to the same extent as opioids or other analgesics. In simpler terms, this means that CBD can help to alleviate pain and that the effects may be lasting, without the need for increasing doses over time. However, the best dose can vary according to the change in intensity of pain, type of medicine, and practices in one’s life.

5. Does taking topical CBD products help with arthritis, or any localized pain in general?

Emerging research says yes! Human research also confirms that CBD topical products are safe for use and effectively relieve arthritis pain and inflammation. Topical CBD affects the targeted area rather than the entire system as it is absorbed by the skin without entering the bloodstream. Just make sure you are using high quality topicals designed to penetrate skin or else it will not be effective.

The Bottom Line

CBD oil has been reported to possess anti-inflammatory and analgesic properties which may effectively manage pain of inflammatory as well as neuropathic nature without leading to addiction. However, still consult with your doctor regarding the possibilities, especially when on other medications that might have cross interactions. CBD oil may not be a panacea for chronic pain, but it might give those suffering from pain some much-needed pain relief in case they design a comprehensive pain management strategy.

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